Wellbutrin and Alcohol: Side Effects and Risks

Key Takeaways

Mixing Wellbutrin and alcohol can be risky, potentially increasing the chance of seizures, mood swings, and poor decision-making.
Wellbutrin may reduce alcohol cravings, making it helpful for some people trying to quit or cut back — but this should only be done under medical supervision.
Some people report unusual reactions to alcohol after starting Wellbutrin, including getting drunk faster or feeling more depressed afterward.
Everyone responds differently, so it’s important to talk to a healthcare provider before combining the two.

At Avenues Recovery, the premier addiction rehabilitation expert, we recognize the complexities individuals face when dealing with both substance abuse and mental health issues. It’s not uncommon for our clients to have questions about how Wellbutrin, a medication used for depression, interacts with alcohol. In this article, we aim to provide you with insight into the use of Wellbutrin alongside alcohol, addressing its safety, potential risks, and the interplay between Wellbutrin and alcohol. Mixing alcohol with Wellbutrin can lead to serious risks, including increased chances of seizures and other dangerous side effects, which we will discuss in detail.

What Is Wellbutrin?

Wellbutrin, known generically as bupropion, is an atypical antidepressant commonly prescribed to treat major depressive disorder and seasonal affective disorder. Wellbutrin can be addictive. Unlike other antidepressants, Wellbutrin works differently by targeting the central nervous system and increasing the levels of norepinephrine and dopamine—two key neurotransmitters that influence mood, motivation, and energy levels. Wellbutrin functions as a norepinephrine-dopamine reuptake inhibitor (NDRI), blocking the reabsorption of these neurotransmitters in the brain. The medication comes in several formulations, including immediate-release, sustained-release, and extended-release tablets. As a norepinephrine dopamine reuptake inhibitor, Wellbutrin can help improve symptoms of depression and is also used to support smoking cessation.

Because Wellbutrin works on different pathways in the brain compared to other antidepressants, it may offer benefits for those who haven’t responded to traditional treatments. Wellbutrin is also sometimes prescribed off-label for conditions such as attention deficit hyperactivity disorder (ADHD). However, taking Wellbutrin comes with potential side effects, and it’s especially important to be cautious when drinking alcohol. Combining Wellbutrin with alcohol can increase the risk of serious side effects and may interfere with the medication’s ability to treat major depressive disorder or other conditions. Complete abstinence from alcohol is the safest approach for anyone taking Wellbutrin. Always consult your healthcare provider before making any changes to your medication or drinking habits.

Can You Drink on Wellbutrin?

No, you should not drink alcohol while on Wellbutrin. In the realm of medication and substance use, safety always takes precedence. Mixing Wellbutrin, an antidepressant, with alcohol carries inherent risks, altering the effects of Wellbutrin and potentially leading to unpredictable and adverse outcomes. To ensure your well-being, it’s strongly advised to consult with a medical professional or your prescribing doctor before even contemplating the combination of Wellbutrin and alcohol, and be sure to discuss any other medications you are taking. The risks far outweigh any perceived benefits, and your health is too precious to compromise.

Wellbutrin and Alcohol Side Effects and Risks

When Wellbutrin and alcohol are mixed, they enhance each other’s side effects, creating a potentially dangerous combination. The liver may struggle to process both substances effectively, resulting in reduced processing of each. This can increase the risk of liver damage, especially in individuals with pre-existing liver disease. Regular monitoring of liver function is recommended for individuals taking Wellbutrin and consuming alcohol. This slower processing can lead to heightened side effects and an increased risk of overdose and intoxication.

Common Wellbutrin side effects with alcohol include:

Dizziness
Drowsiness
Sedation
Confusion
Impaired judgment
Impaired motor skills and coordination
Nausea and/or vomiting
Increased risk of seizures
High blood pressure

Both alcohol and bupropion individually depress the central nervous system. When taken together, there’s a risk of overdose, which can lead to severe symptoms like respiratory depression, a life-threatening condition depending on the amount of alcohol and Wellbutrin consumed. Repeated mixing of Wellbutrin and alcohol can have long-term consequences, such as chronic liver damage and worsening mental health.

Alcohol can also interfere with Wellbutrin’s ability to mitigate depression and ADHD symptoms. This can exacerbate depression and may even cause more depressive symptoms in those without a prior diagnosis. This can significantly disrupt daily life and increase the risk of suicidal thoughts.

The combination of Wellbutrin and alcohol also increases the likelihood of seizures due to its impact on brain function and nerve cell communication. Withdrawal from Wellbutrin and alcohol may also manifest seizures and other symptoms, emphasizing the need for professional treatment to make the withdrawal process as safe and comfortable as possible.

Skipping a Day of Wellbutrin to Drink Alcohol

It’s essential to note that skipping a day of Wellbutrin to consume alcohol is not smart. Stopping bupropion abruptly can lead to withdrawal symptoms and increase the risk of adverse effects. Alcohol stays in the system for some time after the last drink, which can lead to adverse reactions when taking Wellbutrin the following day. Overdose is a very real risk with this combination, making it best to avoid alcohol while using prescription drugs. Your well-being should always be a top priority, and responsible choices are crucial for your safety.

If you experience severe symptoms after mixing alcohol and Wellbutrin or after stopping bupropion, seek emergency help immediately.

What Does the Wellbutrin and Alcohol Interaction Look Like?

The interaction between Wellbutrin and alcohol can vary from person to person, leading to unpredictable outcomes. Alcohol may reduce the effectiveness of Wellbutrin, potentially resulting in mood swings or emotional instability. Some individuals may attempt to self-medicate with alcohol to cope with these symptoms, which can actually worsen their condition. Additionally, alcohol can impair judgment, potentially increasing the risk of making poor decisions. Impaired decision-making may also lead to consuming more alcohol, further increasing the risk of adverse effects.

Can Wellbutrin Help with Alcoholism?

While the FDA has not specifically approved Wellbutrin to treat Alcohol Use Disorder (AUD), doctors have explored its impact on alcohol dependence and cravings. Wellbutrin alters two crucial neurotransmitters in the brain, dopamine and norepinephrine, which are linked to reward circuits and addiction.

Wellbutrin may help reduce alcohol cravings and withdrawal symptoms, making it more manageable for people to maintain sobriety. However, Wellbutrin should always be used in conjunction with other proven treatments, like counseling or support groups, as its effectiveness in treating alcoholism can vary from person to person.

It’s important to be aware that there may be adverse effects and drug interactions, and Wellbutrin may not be suitable for everyone. As mentioned earlier, combining bupropion and alcohol can lead to serious complications, especially for those with a history of alcohol abuse or seizure disorders. Therefore, individuals struggling with alcoholism should consult with a licensed healthcare provider and ensure they have a valid Wellbutrin prescription with proper medical supervision before considering Wellbutrin as a treatment option.

Furthermore, relying only on medication for alcoholism is not enough. For the most effective results in addressing alcoholism, a comprehensive approach to addiction treatment is recommended, which includes psychotherapy services, counseling, and social support.

Taking Wellbutrin for Alcohol Cravings

Wellbutrin’s potential to reduce alcohol cravings can be a valuable tool for those struggling with alcoholism. It can help with managing the desire for alcohol and potentially increase the chances of achieving sobriety. The extended-release formulation of Wellbutrin may provide more consistent control of cravings throughout the day, offering a prolonged release pattern compared to immediate-release versions. However, the effectiveness of using Wellbutrin to decrease alcohol cravings varies among individuals, highlighting the importance of individualized treatment plans.

Treatment Options for Alcohol and Wellbutrin Abuse

If you’re grappling with alcohol and Wellbutrin abuse, seeking professional help is crucial. At Avenues Recovery, we provide a range of treatment options, including:

Medical detox
Counseling
Rehabilitation programs

These are designed to address the multifaceted needs of individuals facing dual challenges. Individuals with co-occurring conditions such as eating disorders, head injury, or bipolar disorder may require specialized treatment approaches. Our expert team develops personalized treatment plans tailored to your unique situation, ensuring a path towards recovery that is comprehensive and effective.

Wellbutrin and Alcohol Addiction Treatment at Avenues Recovery

If you or a loved one is struggling with Wellbutrin and alcohol abuse, do not hesitate to reach out to Avenues Recovery for the support and guidance you need on your journey to recovery. Our staff are highly trained and experts in the field of addiction. We have helped thousands of people turn their lives around, and we can help you too. Your well-being is our priority, and we are here to help you every step of the way. Contact us today to experience high-quality, professional help and encouragement on your path to sobriety.

FAQs: Drinking Alcohol While on Wellbutrin

How long after taking bupropion can you drink alcohol?

You should wait at least 24 to 48 hours after stopping bupropion before drinking alcohol. This allows the drug to begin clearing from your system and lowers the risk of side effects like seizures or mood changes. Always consult your doctor before combining alcohol and medications.

What happens if you drink alcohol while taking Wellbutrin?

Drinking alcohol while taking Wellbutrin can increase the risk of seizures, agitation, impaired judgment, and worsened depression or anxiety. Some people also report getting drunk faster or experiencing unexpected emotional reactions.

Can Wellbutrin help reduce alcohol cravings?

Yes. Wellbutrin may help reduce alcohol cravings in some people, particularly those with depression or who are trying to cut back. However, it is not officially approved for alcohol use disorder, and results can vary.

Is it safe to occasionally drink while on bupropion?

No, drinking while on bupropion carries risks, even in small amounts. While some people tolerate it, others experience severe side effects. If you choose to drink, it should be done cautiously — and only after discussing it with your healthcare provider.

Why does Wellbutrin make me feel drunk faster?

Wellbutrin can alter how your brain processes alcohol, making you feel intoxicated more quickly or unpredictably. This effect varies by person and can increase the risk of accidents or poor decisions.

Wellbutrin and Alcohol: Risks & Side Effects